Immunity
Helps support your body’s natural
defenses, protect cells from free
radicals, and maintain a healthy
immune response
Maintaining your immune system is crucial because it protects you from harmful substances, germs, and cell changes that can make you feel ill. Many different factors can activate your immune system, which the body does not recognize as its own¹. These are called antigens, and when they attach to special receptors on immune cells, a series of processes are triggered in the body.
As a result, the body stores information about the antigens, learning how to fight them¹,². Because the immune system is constantly learning and adapting, keeping it functioning well is essential to preventing infections and other diseases that could harm your body in the long run¹.
However, we all experience moments throughout the year when our immune system is not working at its best, making us more prone to infections or illness. Luckily, there are supplements with ingredients that can help maintain our defenses and boost immune system function, even in challenging or stressful situations.
Holiby™ Immunity products
Our formula contains a carefully curated blend of ingredients, each chosen for its exceptional ability to support and enhance the immune system. These components work in synergy to provide your body with the natural defenses it needs to stay strong and resilient, offering a holistic approach to boosting your immune health.
Reishi Mushroom
Elderberry extracts
Astragalus root
Echinacea extracts
Zinc Gluconate
featuring a blend of ingredients like ashwagandha, American ginseng, Rhodiola rosea, maca root, vitamin C, green tea extracts, and vitamin B12—are designed to help ease fatigue, especially on stressful days.
How to Use It, and Who Would Benefit?
Take one or two Holiby Immunity Gummies anytime during the day, ideally with or after meals for better absorption and to prevent stomach upset
For Immunity Drops, shake well and take 2 full droppers (2ml) once or twice daily, either directly or mixed into your favorite drink for quick immune support.
Holiby’s Immunity Supplements are ideal for any adults seeking immune support, especially during seasonal changes, high-stress times, or increased exposure. Perfect for busy individuals, travelers, and those wanting extra wellness protection.
Why It Stands Out?
Meet our Scientist:
Maria Alejandra Tangarife
Relevant expertise:
- InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. In brief: The innate and adaptive immune systems. [Updated 2023 Aug 14]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279396/
- InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. In brief: How does the immune system work? [Updated 2023 Jun 6]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279364/
- Chang, Y. H., Yang, J. S., Yang, J. L., Wu, C. L., Chang, S. J., Lu, K. W., Kuo, C. L., Hsia, T. C., & Chung, J. G. (2009). Gandoderma lucidum extract promotes immune responses in normal BALB/c mice In vivo. In vivo (Athens, Greece), 23(5), 755–759.
- Wang, X., & Lin, Z. (2019). Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism. Advances in experimental medicine and biology, 1182, 1–37. https://doi.org/10.1007/978-981-32-9421-9_1
- Li, K., Liu, W., Wu, C., Wang, L., Huang, Y., Li, Y., Zheng, H., Shang, Y., Zhang, L., & Chen, Z. (2024). The anti-fatigue and sleep-aiding effects vary significantly among different recipes containing Ganoderma lucidum extracts. Heliyon, 10(10), e30907. https://doi.org/10.1016/j.heliyon.2024.e30907
- Yuen, M. F., Ip, P., Ng, W. K., & Lai, C. L. (2004). Hepatotoxicity due to a formulation of Ganoderma lucidum (lingzhi). Journal of hepatology, 41(4), 686–687. https://doi.org/10.1016/j.jhep.2004.06.016
- Liu, D., He, X. Q., Wu, D. T., Li, H. B., Feng, Y. B., Zou, L., & Gan, R. Y. (2022). Elderberry (Sambucus nigra L.): Bioactive Compounds, Health Functions, and Applications. Journal of agricultural and food chemistry, 70(14), 4202–4220. https://doi.org/10.1021/acs.jafc.2c00010
- Tiralongo, E., Wee, S. S., & Lea, R. A. (2016). Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial. Nutrients, 8(4), 182. https://doi.org/10.3390/nu8040182
- Hawkins, J., Baker, C., Cherry, L., & Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary therapies in medicine, 42, 361–365. https://doi.org/10.1016/j.ctim.2018.12.004
- Xue, H., Gan, F., Zhang, Z., Hu, J., Chen, X., & Huang, K. (2015). Astragalus polysaccharides inhibits PCV2 replication by inhibiting oxidative stress and blocking NF-κB pathway. International journal of biological macromolecules, 81, 22–30. https://doi.org/10.1016/j.ijbiomac.2015.07.050
- Wang, X., Wang, R., Qu, Z., Zhu, Y., & Li, Y. (2022) Advances on immunoregulation effect of astragalus polysaccharides. Front. Nat. Prod., 1. https://doi.org/10.3389/fntpr.2022.971679
- Zhang, P., Liu, X., Liu, H., Wang, W., Liu, X., Li, X., & Wu, X. (2018). Astragalus polysaccharides inhibit avian infectious bronchitis virus infection by regulating viral replication. Microbial pathogenesis, 114, 124–128. https://doi.org/10.1016/j.micpath.2017.11.026
- Yeh, T. S., Lei, T. H., Barnes, M. J., & Zhang, L. (2022). Astragalosides Supplementation Enhances Intrinsic Muscle Repair Capacity Following Eccentric Exercise-Induced Injury. Nutrients, 14(20), 4339. https://doi.org/10.3390/nu14204339
- Vieira, S. F., Gonçalves, S. M., Gonçalves, V. M. F., Llaguno, C. P., Macías, F., Tiritan, M. E., Cunha, C., Carvalho, A., Reis, R. L., Ferreira, H., & Neves, N. M. (2023). Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations. Antioxidants (Basel, Switzerland), 12(2), 425. https://doi.org/10.3390/antiox12020425
- Burlou-Nagy, C., Bănică, F., Jurca, T., Vicaș, L. G., Marian, E., Muresan, M. E., Bácskay, I., Kiss, R., Fehér, P., & Pallag, A. (2022). Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review. Plants (Basel, Switzerland), 11(9), 1244. https://doi.org/10.3390/plants11091244
- Karsch-Völk, M., Barrett, B., Kiefer, D., Bauer, R., Ardjomand-Woelkart, K., & Linde, K. (2014). Echinacea for preventing and treating the common cold. The Cochrane database of systematic reviews, 2014(2), CD000530. https://doi.org/10.1002/14651858.CD000530.pub3
- Lin, P. H., Sermersheim, M., Li, H., Lee, P. H. U., Steinberg, S. M., & Ma, J. (2017). Zinc in Wound Healing Modulation. Nutrients, 10(1), 16. https://doi.org/10.3390/nu10010016
- Gammoh, N. Z., & Rink, L. (2017). Zinc in Infection and Inflammation. Nutrients, 9(6), 624. https://doi.org/10.3390/nu9060624
- Hemilä H. (2017). Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. JRSM open, 8(5), 2054270417694291. https://doi.org/10.1177/2054270417694291
- Age-Related Eye Disease Study 2 Research Group (2013). Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA, 309(19), 2005–2015. https://doi.org/10.1001/jama.2013.4997
- LeBoff, M. S., Chou, S. H., Ratliff, K. A., Cook, N. R., Khurana, B., Kim, E., Cawthon, P. M., Bauer, D. C., Black, D., Gallagher, J. C., Lee, I. M., Buring, J. E., & Manson, J. E. (2022). Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults. The New England journal of medicine, 387(4), 299–309. https://doi.org/10.1056/NEJMoa2202106
- Heyer, F. L., de Jong, J. J., Willems, P. C., Arts, J. J., Bours, S. G. P., van Kuijk, S. M. J., Bons, J. A. P., Poeze, M., Geusens, P. P., van Rietbergen, B., & van den Bergh, J. P. (2021). The Effect of Bolus Vitamin D3 Supplementation on Distal Radius Fracture Healing: A Randomized Controlled Trial Using HR-pQCT. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 36(8), 1492–1501. https://doi.org/10.1002/jbmr.4311
- Daryabor, G., Gholijani, N., & Kahmini, F. R. (2023). A review of the critical role of vitamin D axis on the immune system. Experimental and molecular pathology, 132-133, 104866. https://doi.org/10.1016/j.yexmp.2023.104866